Kevin K Brown Selected Research

carlumab

12/2015

CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab.

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Kevin K Brown Research Topics

Disease

52	Idiopathic Pulmonary Fibrosis 01/2022 - 01/2004
24	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 05/2004
20	Disease Progression 01/2021 - 01/2004
14	Fibrosis (Cirrhosis) 01/2022 - 12/2004
12	Lung Diseases (Lung Disease) 01/2020 - 05/2004
8	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2018 - 03/2002
7	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 01/2019 - 01/2006
6	Dyspnea (Shortness of Breath) 01/2015 - 09/2003
5	Vascular Diseases (Vascular Disease) 01/2022 - 05/2004
5	Pulmonary Hypertension 01/2019 - 09/2003
5	Connective Tissue Diseases (Connective Tissue Disease) 05/2014 - 07/2006
5	Vasculitis (Vasculitides) 12/2012 - 10/2002
5	Bronchiectasis 01/2009 - 03/2002
4	Pneumonia (Pneumonitis) 01/2021 - 01/2004
4	Inflammation (Inflammations) 01/2014 - 03/2002
3	Infections 01/2022 - 09/2003
3	Systemic Scleroderma (Systemic Sclerosis) 12/2021 - 03/2011
3	Neoplasms (Cancer) 01/2021 - 08/2013
3	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 11/2020 - 11/2013
3	Idiopathic Interstitial Pneumonias 01/2020 - 06/2009
3	Rheumatoid Arthritis 01/2020 - 05/2009
3	Tuberous Sclerosis (Bourneville's Disease) 01/2019 - 09/2010
3	Lung Injury 01/2018 - 01/2007
3	Pulmonary Arterial Hypertension 06/2016 - 06/2008
3	Bronchiolitis 06/2013 - 05/2004
3	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 12/2012 - 01/2006
3	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 12/2012 - 02/2006
3	Churg-Strauss Syndrome (Allergic Angiitis) 12/2012 - 01/2006
3	Microscopic Polyangiitis 12/2012 - 01/2006
2	Diarrhea 10/2019 - 05/2014
2	Cough 01/2017 - 03/2013
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2017 - 01/2004
2	Bronchiolitis Obliterans 06/2013 - 05/2004
2	Emphysema 09/2010 - 09/2005
2	Acute Lung Injury 06/2007 - 09/2006
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2022
1	Body Weight (Weight, Body) 04/2021
1	COVID-19 01/2021
1	Rheumatic Diseases (Rheumatism) 09/2017

Drug/Important Bio-Agent (IBA)

14	nintedanibIBA 01/2022 - 09/2011
10	CollagenIBA 01/2022 - 05/2004
8	Carbon MonoxideIBA 01/2022 - 09/2003
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2009
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2012
6	Pharmaceutical PreparationsIBA 01/2022 - 05/2004
5	AntibodiesIBA 01/2020 - 08/2004
5	lipoarabinomannan (LAM)IBA 01/2019 - 09/2010
5	Bleomycin (Blenoxane)FDA LinkGeneric 01/2018 - 01/2007
4	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2015 - 01/2004
4	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 12/2012 - 01/2006
3	Mycophenolic Acid (Cellcept)FDA LinkGeneric 12/2021 - 07/2006
3	AntigensIBA 11/2020 - 11/2013
3	AutoantibodiesIBA 01/2020 - 05/2009
3	Sirolimus (Rapamycin)FDA Link 01/2019 - 04/2011
3	Biological ProductsIBA 01/2019 - 01/2009
3	ambrisentan FDA Link 11/2015 - 05/2013
3	Oxygen (Dioxygen)IBA 01/2015 - 09/2003
3	beta-cyclodextrin tetradecasulfate (CTDS)IBA 05/2014 - 07/2006
3	Bosentan (Tracleer)FDA Link 07/2011 - 01/2008
3	Surface-Active Agents (Surfactants)IBA 06/2009 - 01/2007
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2021
2	simtuzumabIBA 01/2020 - 01/2017
2	trans-sodium crocetinate (crocetin)IBA 01/2019 - 09/2010
2	Tyrosine Kinase InhibitorsIBA 09/2017 - 09/2011
2	Matrix Metalloproteinase 7 (Matrilysin)IBA 12/2013 - 03/2002
2	MucinsIBA 12/2013 - 04/2011
2	Vascular Endothelial Growth Factor DIBA 08/2013 - 09/2010
2	Endothelin Receptor AntagonistsIBA 02/2010 - 06/2008
2	DNA (Deoxyribonucleic Acid)IBA 01/2007 - 09/2003
2	Antigen-Antibody Complex (Immune Complex)IBA 02/2006 - 01/2006
1	RNA (Ribonucleic Acid)IBA 04/2022
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2021
1	Immunoglobulin A (IgA)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 10/2019
1	Tyrosine (L-Tyrosine)FDA Link 10/2019
1	anti-scl-70 autoantibodiesIBA 01/2019
1	Bronchodilator Agents (Bronchodilators)IBA 01/2019
1	GLPG1690IBA 01/2019
1	penicillamine-glutathione mixed disulfideIBA 01/2018
1	Complement C3 (C3 Complement)IBA 01/2018
1	indium-bleomycinIBA 01/2018
1	Protein SIBA 01/2018
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2018
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2017
1	Galectin 3 (LGALS3)IBA 06/2016
1	Monoclonal AntibodiesIBA 01/2016
1	pirfenidoneIBA 01/2016
1	pamrevlumabIBA 01/2016
1	Desmoplakins (Desmoplakin)IBA 01/2016
1	Connective Tissue Growth FactorIBA 01/2016
1	LigandsIBA 12/2015
1	carlumabIBA 12/2015
1	CC ChemokinesIBA 12/2015
1	Protease Inhibitors (Protease Inhibitor)IBA 10/2015

Therapy/Procedure

24	Therapeutics 04/2021 - 01/2004
3	Traction 01/2009 - 08/2007
2	Lung Transplantation 10/2008 - 01/2006
1	Radiotherapy 01/2022
1	Drug Tapering 04/2021
1	Intravenous Infusions 01/2016